Course book Advanced Treatment Planning 2018
The Volume Effect in OAR
1
Parallel
V
a
reference
VD
VD
(
)
=
(
)
irradiated
reference
V
irradiated
20
Relative Tolerance Dose
10
5
1
0.1
0.5
0.5
1/ a
Fraction of Irradiated Volume
Serial
0
1
Adapted and redrawn from: Marks LB, et al. Use of normal tissue complication probability models in the clinic. Int. J. Radiat. Oncol. Biol. Phys. 2010 (76-3): S10-S19.
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