Course book Advanced Treatment Planning 2018
How to consider the volume effect in dose-response models?
2
x
DD
−
1
(
)
−
t
50
2
NTCP
dx e t
=
=
2
•
Probit : Lyman
50
D
−
2
50
1
j = = 1
a
a j j Dv
EUD
1
NTCP
=
•
Logistic (log dose ): Niemierko
4
50
D
1
+
D
50
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