Course book Advanced Treatment Planning 2018
Reliability of radiobiological evaluation • Solution 1: different populations, different parameters to be used in dose-response model (Lyman)
1.0
Sequential CRT
Concomitant CRT
TD
46 (42 – 50)
TD
36 (34 – 56)
50
50
0.5
2.7 (1.25 – 5)
0.95 (0.71 – 1.11)
50
50
a
3.4 (2.4 – 5)
a
11.1 (1.3 – 14.3)
NTCP [*100 %]
0
0
40
80
120
Dose [Gy]
J Zhu et al. Analysis of acute radiation-induced esophagitis in non-small-cell lung cancer patients using the Lyman NTCP model. Radiother Oncol (2010) 449–454.
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