Course book Advanced Treatment Planning 2018
Parameters for clinical outcome: Salivary glands
Irradiation type (partial organ unless otherwise stated)
Dose (Gy), or dose/volume parameters
Volume segmented
Notes on dose/volume parameters
Endpoint
Rate (%)
Long term parotid salivary function reduced to <25% of pre- RT level Long term parotid salivary function reduced to <25% of pre- RT level Long term parotid salivary function reduced to <25% of pre- RT level
Bilateral whole parotid glands
For combined parotid glands
3D-CRT
Mean dose <25
<20
Unilateral whole parotid gland
For single parotid gland. At least one parotid gland spared to <20 Gy
3D-CRT
Mean dose <20
<20
For combined parotid glands
Bilateral whole parotid glands
3D-CRT
Mean dose <39
<50
• Severe xerostomia is related to additional factors including the doses to the submandibular glands • But submandibular glands should be included in the CTV for Ib nodes irradiation (oropharynx, oral cavity, N3)
Deasy JO et al. Radiation Dose-Volume effects on the salivary gland function. Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S58–S63, 2010.
Made with FlippingBook - Online Brochure Maker