Course book Advanced Treatment Planning 2018
Parameters for clinical outcome: Small bowel
Baglan-Robertson threshold model for risk of acute small bowel toxicity
500
450
400
100 individual bowel loops [cc] 150 250 300 350
High risk (≈40%) of G3 or worse acute toxicity
CTCAE G3 : Abdominal pain, fever, change in bowel habits with ileus; peritoneal signs
200 50 paralysis (Gy)
ED
Absolute Volume of
Low risk (≈10%)of G3 or worse acute toxicity
50
Cord length [mm]
0
0
5
10
15
20
25
30
35
40
45
Dose (Gy)
Kavanagh BD et al. Radiation Dose-Volume effects in the stomach and small bowel. Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S101–S107, 2010.
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