Course book Advanced Treatment Planning 2018
Parameters for clinical outcome: Rectum
• Dose-Volume histogram ( DVH ) against Dose-Wall Histogram ( DWH )
DWH better predicts Rectal Toxicity than DVH
The difference in model accuracy is not so high AvAUC DVH = 0,73 AvAUC DWH = 0,76
• Toxicity scored with a modified RTOG score • Endpoint G2 or higher within 2 years from the end of the treatment
Tucker SL et al. Comparison of rectal dose-wall histogram versus dose-volume histogram for modeling the incidence of late rectal bleeding after radiotherapy. Int J Radiat Oncol Biol Phys 2004;60:1589–601.
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