Course book Advanced Treatment Planning 2018

Can we derive an internal target volume from 3D PET?

12 NSCLC scheduled for SBRT; 4D PET/CTs, 4 observers:

1. ITV in 4D CT „gold standard“

30

2. „GTVs“ in 3D PET 3. ITVs from 4D PET

25

20

15

ITV-4D CT

- manual - Homburg algorithm - Rover algorithm

3D-GTV-PET

ml

ITV- 4D PET

10

5

- 40% SUVmax - 15% SUVmax

0

manual mean HOM Rover

40% 15%

26