Course book Advanced Treatment Planning 2018

Hypoxia Dose Painting Trail in Tübingen, Germany

HV PTV70 PTV60 PTV54

• Definition of hypoxic volume (HV) according to [ 18 F]- FMISO PET/CT

• Dose escalation of 10%

(77Gy) in the HV inside the PTV70 in the experimental treatment arm

• Isotoxic approach!

• So far n=26 patients included.

IMRT plan for patient #3 in the HDP trial.

7| D. Thorwarth | 06.04.2014 ESTRO 33