IMRT 2018

Fiorino et al. 2011

Prospective study (> 500 pts), self-reported questionnaires Taking into account severity and duration of symptoms V40 > 80%: predictor of Mean Incontinence Score together with previous bowel symptoms, antihypertensive drugs, surgery Two patterns for occurrence of faecal incontinence after RT: 1: consequent to acute effects and mainly responsible for peak events (ca ½ pts recovering from symptoms) 2: needs longitudinal analysis - it results form the irradiation of large fraction of the rectum at intermediate doses (V40), presence of pre-treatment bowel symptoms, previous abdominal-pelvivc surgery for chronic incontinence - Vascular damage, more than damage to sacral nerve (hypertensive drugs work)

06/06/2018