IMRT 2018
Second Cancers: IMRT vs. 3-D conformal RT
Key is the shape of the dose-response relationship for radiation-induced carcinogenesis...
High doses don ’ t matter
High doses do matter
OR
Cancer Risk
total dose
total dose
• IMRT minimizing high doses helps • IMRT ’ s extra lower doses less important
• IMRT minimizing high doses doesn ’ t help • IMRT ’ s extra lower doses are bad
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