IMRT 2018

NTCP Models for Patient-Reported Outcomes after 3DCRT

▪ Moderate to severe xerostomia as assessed by the EORTC QLQ-H&N35 at 6 months after completing RT of CHRT ▪ Moderate to severe sticky saliva at 6 months

▪ All organs at risk (OARs) potentially involved in salivary function were delineated on planning-CT, including the parotid, submandibular and sublingual glands and the minor glands in the soft palate, cheeks and lips ▪ Patients with moderate to severe xerostomia or sticky saliva at baseline were excluded

Beetz I, Schilstra C, Burlage FR, et al. Development of NTCP models for head and neck cancer patients treated with three-dimensional conformal radiotherapy for xerostomia and sticky saliva: the role of dosimetric and clinical factors. Radiother Oncol. 2012 Oct;105(1):86-93.