IMRT 2018

Optic Neuropathy Risk - Synopsis

A TD of 45Gy/SD 1.8 Gy and RS with 1 x 8 Gy seem to be completely safe

At TD 50-60Gy/SD <2 Gy and RS with 1 x 10-12 Gy a low incidence of ON is reported

At TD>60Gy with SD < 2 Gy and TD>50 Gy with SD >2 Gy as well as RS with >12 Gy,

ON risk increases quickly with dose and SD