Molecular Imaging 2017

Perfusion & Angiogenesis Hypoxia

DCE-MRI Parameters indirectly reflect perfusion, hypoxia & the functioning microvasculature

K trans

k ep

v e

Dynamic contrast enhanced MRI

Intrinsic susceptibility weighted MRI Sensitive to paramagnetic deoxyhemoglobin in red blood cells in perfused vessels Provides information of red cell delivery & level of blood oxygenation

T2

ADC

Intrinsic susceptibility weighted MRI