Molecular Imaging 2017

The PROMIS study

 mP-MRI prior to biopsy  Recruitment: 740 males (target 715)

 TPM (reference standard) & TRUS biopsy (current standard)  To assess the ability of MP-MRI to identify men who can safely avoid unnecessary biopsy  To assess the ability of the MP-MRI based pathway to improve the rate of detection of clinically significant cancer as compared to TRUS biopsy  To estimate the cost-effectiveness of an MP-MRI based diagnostic pathway

El-Shater Bosaily et al. Contemp Clin Trials. 2015 May;42:26-40