Molecular Imaging 2017

Optimal time for response assessment ?

SSP RC versus non RC à S26

SSP RC versus non RC à S11

HR = 0,21 ; IC

: 0,15-0,29 (p < 0,001)

HR = 0,71 ; IC

: 0,53-0,95 (p = 0,02)

95

95

100

100

83 %

80 %

80

80

72 %

60

60

40

40

45 %

SSP (%)

PR CR

SSP (%)

PR CR

20

20

0 1 2 3 4 5 6 7 8 9 10 0

0

Years 0 1 2 3 4 5 6 7 8 9 10

Years

Response assessment at W11 seemed too early : 60 % of patients considered with partial response at S11 were in complete remission at W26

ASCO ® 2012 - D ’ après Glynne-Jones R et al., abstr. 4004 actualisé

Except in the case of progression, it is necessary to wait until 4-6 months after the end of radiochemotherapy, before discussing a salvage surgery in case of residual tumor