Molecular Imaging 2017

Can we derive an internal target volume from 3D PET?

• 12 NSCLC scheduled for SBRT; 4D PET/CTs, 4 observers:

• 1. ITV in 4D CT „gold standard“

30

• 2. „GTVs“ in 3D PET • 3. ITVs from 4D PET

25

20

- manual - Homburg algorithm - Rover algorithm

15

ITV-4D CT

3D-GTV-PET

ml

ITV- 4D PET

10

- 40% SUVmax - 15% SUVmax

5

0

manual mean

HOM

Rover

40%

15%

34