Imaging for early stage breast cancer

Histological Grade

Scarff-Bloom-Richardson Score modified by Elston & Ellis

Tubule formation Majority of tumour Moderate degree

(>75%) - 1 point (10-75%) - 2 points (<10%) - 3 points

Little or none

Nuclear pleomorphism* Small, regular uniform cells - 1 point Moderate increase in size and variability - 2 points Marked variation - 3 points * Reference point - normal epithelial cells Mitotic counts - 1 - 3 points Dependent on microscope field area

Elston&Ellis Histopathology 1991