ClearLLab LS CaseBook

This CD5/CD19 dot plot is gated on Lymphocytes. In addition to CD5 positive, CD19 negative T lymphocytes and a very small populationof CD5negative, CD19positivenormal B lymphocytes, a prominent aberrant CD5 and CD19 dual positive population is present. This aberrant population corresponds to the Lambda immunoglobulin-restricted population noted earlier in this analysis, whereas the other B lymphocytes correspond to the polyclonal population.

This CD56/Side Scatter dot plot is gated on CD45+ events. Unlike the dot plots gated on Lymphocytes, it includes the named populations defined on the CD45/Side Scatter dot plot: lymphocytes (red), monocytes (green), granulocytes (blue), and blasts (pink). This dot plot demonstrates a small populationwith low side scatter light properties that expresses CD56, consistent with apparent NK cells.

This CD34/Side Scatter dot plot is gated on CD45+ events. Unlike the dot plots gated on Lymphocytes, it includes the named populations defined on the CD45/Side Scatter dot plot: lymphocytes (red), monocytes (green), granulocytes (blue), and blasts (pink). No significant CD34 positive population is present.

This CD10/Side Scatter dot plot is gated on CD45+ events. Unlike the dot plots gated on Lymphocytes, it includes the named populations defined on the CD45/Side Scatter dot plot: lymphocytes (red), monocytes (green), granulocytes (blue), and blasts (pink). Granulocytes (blue) are positive for CD10.

NeoplasticProcessofBcellOrigin > Chronic lymphocytic leukemia/small lymphocytic lymphoma > Case#6:ChronicLymphocyticLeukemia/SmallLymphocyticLymphomaLymphocyticLymphoma

Every Event Matters

51

Beckman Coulter • ClearLLab LS Casebook