Proefschrift Kerklaan

CONTENTS

PART I.

INTRODUCTION

Chapter 1.

General introduction

9

PART II.

CURRENT NUTRITIONAL PRACTICES

Chapter 2.

Worldwide survey of nutritional practices in PICUs

31

PART III. Chapter 3.

ENERGY EXPENDITURE

measurements to determine

55

Validation of ventilator-derived VCO 2

energy expenditure in ventilated critically ill children

Chapter 4.

Use of indirect calorimetry to detect overfeeding in critically ill children;

69

finding the appropriate definition

PART IV. Chapter 5.

SUPPLEMENTAL PARENTERAL NUTRITION

Evidence for the use of parenteral nutrition in the pediatric intensive

87

care unit

Chapter 6.

Impact of withholding early parenteral nutrition completing enteral nutrition in pediatric critically ill patients (PEPaNIC trial): study protocol for a randomized controlled trial Early versus late parenteral nutrition in critically ill children

105

Chapter 7.

123

PART V.

DISCUSSION AND SUMMARY

Chapter 8. Chapter 9.

General discussion

153 177

Summary/Samenvatting

PART VI.

APPENDICES List of abbreviations About the author List of publications

193 195 197 198 201

PhD portfolio Dankwoord