Proefschrift_Holstein

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Chapter 7

Example sessions for two subjects.

1 week

session 1

session 2

session 3

run 1

run 2

run 4

run 5

run 6

run 3

Example subject X

15cent

word

run 1

run 2

run 3

run 4

run 5

run 6

Example subject Y

15cent

word

B Examples of one session for subject X and Y

Baseline (no cTBS) run followed by cTBS run: N = 14

run 1

run 2

fMRI (no cTBS: baseline)

fMRI (cTBS stimulation)

Break - cTBS

15cent

word

Task (~ 32 min)

10.02 (0.19) min

94.02 (0.92) min

cTBS run followed by baseline (no cTBS) run: N = 13

run 1

run 2

fMRI (cTBS stimulation)

fMRI (no cTBS: baseline)

cTBS

Break

15cent

word

Task (~ 32 min)

10.61 (0.29) min

93.27 (0.96) min

84.62 (1.33) min

Figure 7.2 Experimental design A: Across experimental sessions, each participant received stimulation of the anterior prefrontal cortex, dorsolateral PFC, and premotor cortex. The order was counterbalanced between participants (indicated with black, grey and white thunderbolts). Stimulation site order was counterbalanced across participants. Vertical dashed lines indicate a break. B: The order (stimulation and baseline condition) in which a participant would always perform the tasks ( figure 7.3 ) was counterbalanced between participants. Values represent mean (SD) time in minutes (min) between the start of two runs and between cTBS administration and the start of the subsequent fMRI session. In addition, in the bottom panel the mean time (across participants and sessions) between cTBS and the start of the baseline session is specified. cTBS: continuous theta burst stimulation; transcranial magnetic stimulation (TMS).

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