Proefschrift_Holstein

Chapter 3

Table S3.2b Mean response times and error rates on reward and switching for the DAT1 10 R homozygotes ( n = 27)

High reward

Low reward

Repeat 8 (1.20) 320.89 (6.4) 9.95 (1.46) 319.36 (8.91)

Switch 11.8 (1.38) 325.36 (6.81) 11.12 (1.42) 322.97 (9.85)

Repeat 8.21 (1.23) 327.2 (6.85) 11.71 (1.53) 330.93 (9.79)

Switch 14.1 (1.74) 329.88 (7.45) 13.30 (1.83) 328.75 (10.07)

Errors (%) *, 1 (s.e.m.) RT (ms) +, 3 (s.e.m.) Errors (%) *, 2 (s.e.m.) RT (ms) +, 4 (s.e.m.)

Placebo

Bromocriptine

s.e.m. = standard error of the mean Significant effects: * Main effect of switching: F(1,26) = 19.9, p < .001; main effect of reward: F(1,26) = 4.9, p < .04; drug*switching: F(1,26) = 5.4, p < .0.3 1 main effect of switching: F(1,26) = 25.5, p < .001; 2 main effect of reward: F(1,26) = 6.9, p < .02 3 main effect of reward: F(1,26) = 6.4, p < .02; main effect of switching: F(1,26) = 4.4, p <. 05 4 main effect of reward: F(1,26) = 13.7, p < .002; + main effect of reward: F(1,26) = 15.1, p<.001

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