Proefschrift_Holstein

Chapter 4

Bond & Lader mood scales F(1,44) F(1,45) F(1,20) F(1,44) F(1,20) Contentedness 67.42 (4.58) 66.91 (7.15) 76.86 (3.84) 76.82 (4.63) 84.69 (3.50) 77.05 (2.82) F = 8.78; p < .005 MWU =336.5; p > .05 Wc= 50; p = .013 F < 1 F < 1 Alertness 49.36 (4.19) 57.15 (5.90) 71.79 (3.99) 69.38 (4.66) 78.52 (5.15) 69.74 (2.62) F = 22.74; p < .001 F =1.42; p > .05 F =22.73; p < .001 F = 3.58; p > .05 F = 1.96; p > .05 49.46 58.91 62.00 83.40 74.72 F < 1

F = 1.485, p > .05

p > .05

p > .05

MWU = 230;

MWU = 311;

Wc = 122; p > .05 F < 1 F < 1

F < 1

DAT1

MPH x

F = 1.51; p > .05

p > .05

DIAGNOSIS x DAT1

MWU = 356; p > .05 F<1 F < 1

KW (3) = 5.418;

F = 1.14; p > .05

Wc = 150; p = .026

vs. ADHD OFF

F = 1.42; p > .05 F<1 F < 1

ADHD ON

(unless noted otherwise)

MWU =289; p > .05

MWU = 256; p > .05

F = 13.26; p < .001

ADHD OFF ADHD ON HC Univariate or repeated measures GLM 10R/10R 9R carriers 10R/10R 9R carriers 10R/10R ADHD OFF vs. HC ADHD ON vs. HC

MWU = 355.5; p > .05

F = 22.46; p < .001

MWU = 177.5; p = .024

(9.23) F < 1

2.78

42.16

64.31

(2.11)

(6.05)

(0.61)

(3.52)

210.09

2.72

46.89

69.67

(3.66)

(8.51)

(8.41)

(1.12)

(4.56)

204.67

3.82

43.36

53.36

(3.48)

(2.34)

(9.79)

(1.12)

(6.91)

199.73

2.46

55.18

38.18

(3.32)

(0.64)

(6.07)

(3.48)

222.00

(10.36)

5.00

54.27

42.27

(3.44)

(1.05)

(7.75)

(3.21)

204.46

(10.39)

9R

5.09

54.09

Calmness 59.73 (4.44)

37.55

(2.60)

(1.42)

(3.82)

219.64

(13.65)

carriers

Table 4.3 Mood and neuropsychological assessment

Neuropsychological assessment Motor speed (RT, sec) Vigilance (RT) Vigilance (misses)

Verbal fluency

(no. of words)

KW = Kruskal-Wallis test; MWU = Mann Whitney U test; Wc = Wilcoxon paired rank test; MPH = methylphenidate; 10R/10R = 10R homozygotes

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