2016 Hematological Malignancies

HD12 trial design for advanced stages De-escalation of RT possible?

Randomisation

Arm A 8 x B esc

Arm B 8 x B esc

Arm C 4 + 4

Arm D 4 + 4

Central diagnostic panel

30 Gy (initial bulk, residual)

30 Gy (initial bulk, residual)

„no RT“

„no RT“