2016 Hematological Malignancies

HD15 in advanced HL Freedom from Treatment Failure (FFTF)

Freedom from Treatment Failure 0.0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 0 12 p-value A vs. B : 0.009 A vs. C : 0.5

A: 84.4% B: 89.3% C: 85.4%

60 months difference

4.9% 1.1% 3.9%

97.5%-CI: [ 0.5%, 9.3%] 97.5% CI: [-3.7%, 5.8%] 97.5% CI: [-0.5%, 8.2%]

C vs. B : 0.04 (n.s.)

24

36

48

60

72

Time [months]

Engert A et al, Lancet 2012