Microsoft Word - BYLAWS 9_26_10
OMB MEETING MATERIALS
182
False Positive/False Negative Rates/Sensitivity vs. Probability of Detection (POD)
Background About ten years ago, AOAC and others, recognized that the “false positive rates”, “false negative rates”, and “sensitivity” concepts are flawed in several respects: • 1) the concentration level for false positive/negative rate is not usually specified; • 2) the prevalence of the target is not taken into account, specifically, the predictive value for especially low incidence analytes is not considered, • 3) the statistically validity, i.e., the number of samples used to determine is uncontrolled.
08/09/2018
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