SPSFAM EXPERT REVIEW PANEL

1. Are the definitions specified in the SMPR used and applied appropriately in the supporting documentation (manuscripts, method studies, etc...)? If not, please explain the differences and if the method is impacted by the difference. 2. Is there information demonstrating that the method meets the SMPR Method Performance Requirements using the Reference Materials stated in the SMPR? If not, then specify what is missing and how this impacts demonstration of performance of the method. method performs within the SMPR Method Performance REquirements table specifications for all analytes in the SMPR applicability statement? If not, please specify what is missing and whether or not the method's applicability should be modified. 1. Based on the supporting information, were there any additional steps in the evaluation of the method that indicated the need for any additional precautionary statements in the method? 2. Does the method contain system suitability tests or controls as specified by the SMPR? If not, please indicate if there is a need for such tests or controls and which ones. 3. Is there information demonstrating that the method system suitability tests and controls as specified in the SMPR worked appropriately and as expected? If no, please specify. 3. Is there information demonstrating that the

Not applicable.

Not applicable.

Authors did not provide information on 5) system suitability and or analytical control, i.e. the blank checks and check standards. BPA is known to ubiquitous in the environment. It is very important to demonstrate the minimal cross-contamination during the sample preparation and analysis.

I would request information on blank samples, e.g. chromatograms and concentrations found.

Authors provided information on LOD/LOQ, the sample spikes to demonstrate accuracy, and repeatability, but authors need to supplement the data on system suitability and quality control.

No. no information on sample blanks, control samples, or check standards.