Chemistry-PTM-OMA_Modules_1-4

Calculation of LOD and LOQ est From the graph of s r vs. mean cand :

y = 0.0604x + 0.0646

  0.12 3.3 0.0646 1 1.65(0.0604)  

  s m

3.3 1 1.65  

X

LOD =                    =                              = 0.37 ppm 0 b

LOQ est

= 3 x LOD = 3 x 0.37 = 1.1 ppm