Chemistry-PTM-OMA_Modules_1-4

Analyzing Data – Qualitative Method MLV

• First, analyze data from each laboratory and each material individually • Determine POD values and 95 % Confidence Intervals • If method comparison, calculate dPOD C statistically significant differences • Combine data across laboratories and calculate LPOD with 95% confidence  interval for each material • If method comparison, calculate dLPOD C with 95 % confidence intervals and look for any  statistically significant differences • Determine error estimates s r , s L , and s R and report with 95% confidence  intervals. • Determine the p ‐value of the t‐test based on the X 2 distribution and compare  to 0.10 to determine whether the interlaboratory effect, s L , is statistically  significant. This is the homogeneity test of laboratory POD values. with 95 % confidence intervals and look for any