2018 March 16 SPDS

Table with history of use from AHP monograp h 2009 (Upton et al. )

Toxicity & Adulteration

• 1980’s reports of hepatotoxicity associated  with herbal products containing skullcap • Suspected adulteration of skullcap supply  with Teucrium spp. (germander)  • Germander known toxic – attempts to  prohibit sale in 90’s • Adulteration persists…