Radiobiology 2016

Cancer genome sequencing

• >25,000 whole cancer genomes have been sequenced per Feb 27 th 2016 • Total # somatic mutations per individual tumor:

10 2

10 5

10 3

10 4

Medulloblastoma Testicular germline Acute leukemia Carcinoids

Breast Ovary

Lung Melanoma

Colorectal Pancreas Glioma

From Stratton, Science 2011 And COSMIC