Radiobiology 2016

0.5 0.6 0.7 0.8 0.9 1

S = e − α D − β D 2 α = α r 1 + α s ( Short S, Mayes C, Woodcock M, Johns H, Joiner MC (1999). Int J Radiat Biol 75: 847–55. α r D c Low-dose hyper- radiosensitivity

T98G human GBM cells

α r

α s

0.4

Surviving fraction

(

)

0.3 ) e − D D c

− 1

First reported in 1986 in mouse epidermis and kidney

0.2

0

1

2

3

4

5

6

Dose/Gy