Radiobiology 2016

1/03/2016

Relevant factors • Patient -related factors influencing normal tissue reactions • Age • Co-morbidity (e.g. cardiovascular diseases, diabetes) • Genetic syndromes (e.g. Ataxia Telangiectasia) • Infection (e.g. IBD, Crohn’s disease) • Interaction with other treatments (e.g. chemotherapy) • Patient’s general condition • Smoking

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Tumor-related factors

• Stage of disease • Volume of the tumor • Lymphatic spread • Radiation dose • Volume of normal tissue irradiated • Fractionation schedule • Use of concomitant chemotherapy

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