September 2016 SPDS Book

Ginger Medicinal Uses

Pharmacology (WHO)

Cholagogic activity Intraduodenal administration of an acetone extract (mainly essential oils) of ginger root to rats increased bile secretion for 3 hours after dosing. The active constituents of the essential oil were identified as [6]- and [10]-gingerol . Antiemetic activity The antiemetic action of ginger has been attributed to the combined action of zingerones and shogaols . Anti-inflammatory activity In vivo studies have shown that oral administration of ginger extracts decreased rat paw edema. The potency of the extracts was comparable to that of acetylsalicylic acid. [6]-Shogaol inhibited carrageenan-induced paw edema in rats by inhibiting cyclooxygenase activity.