ESTRO Multidisciplinary Management of Breast Cancer 2017

Conclusions for RT after BCS

• Radiotherapy can reduce risks of recurrence and of death from breast cancer • In these trials: – Big absolute benefit in recurrence and breast cancer mortality for pN+ and high-risk pN0 – Moderate absolute benefit in recurrence and possible small benefit in mortality benefit for other pN0 women

– No significant departure from “One-in-four” rule

24 Lancet 2011