13 Oropharynx

286 Oropharynx

Table 12.2: Results of high dose-rate brachytherapy for Cancer of the oropharynx :

Authors

Pts 11 19 15

T

Site B, S

EBRT

HDR Local control rate

Dixit et al. (2) Senan et al. (18) Yu et al. (19)

T3

46-48 Gy

7x3 Gy 7x3 Gy 10x3 Gy

82% 87% 94%

T2-3 T, S T2-3 B, T

45 Gy 50 Gy

B = Base of tongue S = Soft palate T = Tonsil

12 References 1. Crook J, Mazeron JJ, Marinello G, et al. Combined external and interstitial implantation for T1 and T2 epidermoid carcinoma of base of tongue: the Créteil experience. Int J Radiat Oncol Biol Phys 1988; 15 : 105-14. 2. Dixit S, Babbo HA, Rakesh V, Bhavsar. Interstitial high dose rate brachytherapy in head and neck cancers: preliminary results. J Brachyther Int 1997; 13 : 363-10. 3. Esche BA, Haie C, Gerbaulet AP, et al. Interstitial and external beam radiotherapy in carcinoma of the soft palate and uvula. Int J Radiat Oncol Biol Phys 1988; 15 : 619-25. 4. Foote RL, Parsons JT, Mendenhall WM, et al. Is interstitial implantation essential for successful treatment of base of tongue carcinoma? Int J Radiat Oncol Biol Phys 1990; 18 : 1293-8. 5. Harrison LB, Zelefsky MJ, Armstrong JG, et al. Performance status after treatment for squamous cell cancer of base of tongue – A comparison of primary radiation therapy versus primary surgery. Int J Radiat Oncol Biol Phys 1994; 30 : 953-7. 6. Hoffstetter S, Malissard L, Pernot M, et al. Retrospective study of a series of 136 carcinomas of the base of tongue treated in Centre Alexis Vautrin. Bull Cancer Radiother 1996; 83 : 90-6. 7. Horwitz EM, Frazier AJ, Martinez AA, et al. Excellent functional outcome in patients with squamous cell carcinoma of the base of tongue treated with external irradiation and interstitial iodine 125 boost. Cancer 1996; 78 : 948-57. 8. Housset M, Baillet F, Dessard-Diana B, et al. A retrospective analysis of three treatment techniques for T1-2 base of tongue lesions: surgery plus postoperative irradiation, external irradiation plus interstitial implantation and external irradiation alone. Int J Radiat Oncol Biol Phys 1987; 13 : 511-6. 9. Langlois D, Hoffsteitter S, Malissard L, et al. Salvage irradiation of oropharynx and mobile tongue about iridium brachytherapy in Centre Alexis Vautrin. Int J Radiat Oncol Biol Phys 1988; 14 : 849-53. 10. Levendag PC, Schmitz PI, Jansen PP, et al. Fractionated high-dose-rate and pulsed-dose-rate brachytherapy: first clinical experience in squamous cell carcinoma of the tonsillar fossa and soft palate. Int J Radiat Oncol Biol Phys 1997; 38 : 497-506. 11. Lusinchi A, Elkandari Json Y, Gerbaulet A, et al. External irradiation plus curietherapy boost in 108 base of tongue carcinomas. Int J Radiat Oncol Biol Phys 1989; 17 : 1191-7. 12. Mazeron JJ, Langlois D, Glaubiger D, et al. Salvage irradiation of oropharyngeal cancers using Iridium 192 wire implants: 5-year results of 70 cases. Int J Radiat Oncol Biol Phys 1987; 13 : 957-62.

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