Essential Guide azelaic acid

Applications / Anti-acne

The results indicate that the antibacterial activity of azelaic acid is associated with the perturbation of intracellular pH of the orga- nisms.

The use of azelaic acid as anti-acne ingredient is highly favourable compared to the traditional anti-acne ingredients, as the side effects are minimal and can easily be controlled by adjustment of the concentration azelaic acid in the cream or gel.

APPLICABILITY PRODUCTS FOR TREATMENT OF ACNE VULGARIS

COSMETIC USE

MEDICAL DEVICE USE

PHARMACEUTICAL USE

AZELAIC ACID

++

++

++

BENZOYL PEROXIDE

-

-

+

RETINOIDS

+/-

+/-

+

α -HYDROXY ACIDS

++

++

++

ADAPALENE

-

-

++

TARATOZENE

-

-

++

SALICYCLIC ACID

+

+

+

SULPHUR

+

+

+

ANTIBIOTICS + Legend: (++ Strongly recommended / Very suitable) (+ Limited recommended / Suitable) (+/- Limited allowed / Limited suitable) (- Forbidden) - -

FUNCTIONALITY PRODUCTS FOR TREATMENT OF ACNE VULGARIS

COSMETIC FUNCTIONALITY

MEDICAL DEVICE FUNCTIONALITY

PHARMACEUTICAL FUNCTIONALITY

AZELAIC ACID

+

+

++

BENZOYL PEROXIDE

-

+/-

+/-

RETINOIDS

+/-

+/-

+

α -HYDROXY ACIDS

-

-

-

ADAPALENE

-

-

++

TARATOZENE

-

-

++

SALICYCLIC ACID

+/-

+/-

+

SULPHUR

+

+/-

+/-

ANTIBIOTICS + Legend: (++ Strongly recommended / Very suitable) (+ Limited recommended / Suitable) (+/- Limited allowed / Limited suitable) (- Forbidden) - -

Phone : +31 475 20 60 70 • service@azeco-cosmeceuticals.com • www.azeco-cosmeceuticals.com Mussenberg 1 • 6049 GZ Roermond • The Netherlands

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