Brain 17 Vienna

RTOG trial 9508

survival – single brain metastases

100

p=0.039

80

60

4.9

6.5 (months)

40

Linac

WBRT + SRS

Gamma knife

Survival (%)

20

WBRT alone

0

0

6

12

18

24

Time (months)

Radiosurgery for solitary brain metastases Radiosurgery for solitary brain metastases

WBRT

whole brain radiotherapy stereotactic radiosurgery

Andrews et al 2004, Lancet; 363: 1665–72

SRS