ESTRO 2020 Abstract book

S380 ESTRO 2020

OC-0614 Evidence-Based Hypofractionated Radiotherapy Uptake in Europe: An Explorative GIRO- HERO Analysis C. Oliveira 1,2 , N. Defourny 3,4 , C. Gasparotto 3 , B. Tawk 5 , D. Rodin 6,7 , J.M. Borras 8 , C. Grau 9 , Y. Lievens 4,10 1 cancer Center Of Southeastern Canada, Department Of Oncology, Kingston, Canada ; 2 queen's University, Department Of Oncology, Kingston, Canada ; 3 european Society For Radiotherapy And Oncology, Estro, Brussels, Belgium ; 4 ghent University, Ghent, Belgium ; 5 heidelberg Ion Therapy Center Hit- German Cancer Research Center Dkfz, Division Of Molecular & Translational Radiation Oncology, Heidelberg, Germany ; 6 princess Margaret Cancer Centre Toronto, Radiation Medicine Program, Toronto, Canada ; 7 university Of Toronto, Department Of Radiation Oncology, Toronto, Canada ; 8 university Of Barcelona, Department Of Clinical Sciences- Idibell, Barcelona, Spain ; 9 aarhus University Hospital, Department Of Oncology And Danish Centre For Particle Therapy, Aarhus, Denmark ; 10 ghent University Hospital, Department Of Radiation Oncology, Ghent, Belgium Purpose or Objective Although efficacy and safety of hypofractionation (HF) has been demonstrated in randomized clinical trials, evidence uptake into clinical practice varies widely. We previously explored practice patterns in a world-wide survey through the ESTRO Global Impact of Radiotherapy in Oncology (GIRO) initiative. Radiation reimbursement, needs and availability have been evaluated through the ESTRO Health Economics in Radiation Oncology (HERO) project. This explorative analysis aims to evaluate correlations between HF uptake for breast (BC) and prostate (PC) cancer, and bone metastases (BM), and health-economic parameters in Europe. Material and Methods HF uptake for BC, PC and BM was derived from the 2018 GIRO survey for 36 European countries, and defined as hypofractionation preference applied to >75% of patients in different curative and palliative clinical scenarios for BC, PC and BM. Additionally, a joint curative breast and prostate HF uptake parameter applied to ≥50% of clinical scenarios was used. Country-specific information on radiation reimbursement, needs and availability was extracted from HERO project datasets and publications. Publicly available national socio-economic data was retrieved. Associations between hypofractionation uptake and health-economic parameters were tested in an exploratory analysis using Spearman’s correlation, Kruskal Wallis and Mann Whitney U tests. Results HF uptake for BC and PC combined was negatively associated with HF-specific reimbursement (mean rank 16 vs 7.64, p =0.002). In node-negative breast-conserving BC and low-grade PC the negative association with HF-specific reimbursement was lower than in more advanced clinical scenarios, while larger departments predicted HF uptake (0.5, p =0.011; 0.6, p =0.003). For node-negative breast- conserving and mastectomy BC, a positive correlation of HF uptake with self-perceived health (0.4, p =0.03; 0.4, p =0.016) was found. In curative PC, HF was associated with an elderly population (0.4, p =0.01), higher national radiotherapy needs (0.4-0.6, p =0.001- 0.04), larger departments (0.55-0.57, p =0.003-0.004), more radiation oncologists per capita (0.4-0.5, p =0.02- 0.048), and higher proportional radiotherapy expenses (0.6, p =0.02-0.046); a higher risk of poverty was negatively correlated with HF uptake (-0.4--0.5, p =0.007-

0.02). For BM, HF was only correlated to social determinants of health such as urbanization (- 0.5, p =0.02), obesity (0.4-0.5, p =0.01-0.04), alcohol abuse (-0.5, p =0.009-0.02), poverty (-0.4, p =0.03-0.04) and education (0.4, p =0.02). HF uptake in cord compression was not associated with any tested factors. Conclusion Associations between HF uptake and health-economic parameters vary between cancer sites, clinical scenarios and treatment intent, illustrating different mechanisms underlying HF evidence implementation. These insights may help guide continuing education and guideline promotion to attain optimal HF utilization. SP-0615 Mentoring & Sponsorship in Radiation Oncology: Relational and Strategic Career Development. C.D. Fuller 1 1 The University of Texas MD Anderson Cancer Center, Radiation Oncology, Houston, USA Abstract text Mentoring and sponsorship are concepts that are routinely suggested for radiation oncology trainees, but often trainees are left with few practical concrete practices to build mentorship and sponsorship networks. We will review literature regarding mentorship and sponsorship in radiation oncology and medical physics, with an eye towards practical career development in academia and clinical practice using goal-oriented relational approaches. We will discuss issues regarding mentor selection, mentor vs. sponsor support, mentoring models, and approaches to initiate and grow mentoring opportunities for physicians and physicists in early- to mid- career. Finally we will discuss mentoring pitfalls, equity in opportunity, and mentee-to-mentor transitions as use cases. SP-0616 Mentoring K. Tanderup 1 1 Aarhus University Hospital, Department of Oncology, Aarhus C, Denmark Abstract text Mentorship is a relationship where an experienced person helps or guides a less experienced person. The process is meant to help the mentee to actively steer the progress of specific aspects of his/hers life or career. Examples of possible benefits for mentees in a clinical or develop profile Guidance in strategic prioritizing (working hours/tasks, work/life balance etc.) Clarification of competencies Advice on how to strengthen their network. Mentoring is increasingly being acknowledged to be important for organizations as it helps to grow and keep talent in the organization. There is therefore an increasing interest in establishing mentorship programmes in many institutions. The presentation will transport some practical advice on how to set up a structure for a good mentor-mentee process. The session will also engage the audience in the discussion by including small interactive exercises. their academic Symposium: Young lunch symposium: Mentoring academic career are: Feedback on their CV Help to