Quantitative Methods 2017

Grading according CTCAEv4.0

Simple and relatively straightforward endpoints EXAMPLE: Anemia Grading Descriptions Grade 1

Hemoglobin (Hgb)

Hgb <10.0 - 8.0 g/dL; <6.2 - 4.9 mmol/L; <100 - 80g/L Hgb <8.0 g/dL; <4.9 mmol/L; <80 g/L; transfusion indicated Life-threatening consequences; urgent intervention indicated

Grade 2 Grade 3 Grade 4 Grade 5

Death