Quantitative Methods 2017

Clinical relevance xerostomia

Toxicity grading

Quality of life scale

P-value

Grade 0

Grade 1

Grade 2

Grade 3-4

Physical functioning

81

82

75

71

P-0.001

Role functioning

74

74

67

67

P=0.044

Emotional functioning

84

80

74

69

P=0.001

Social functioning

88

85

79

64

P<0.001

Global quality of life

73

75

65

55

P<0.001

Fatigue

25

28

36

42

P<0.001

Little effect Moderate effect Strong effect

Langendijk et al. J Clin Oncol 2008;26:3770-3776