Quantitative Methods 2017

STEP 3: Integrate step 1 and 2 Translate Δdose è ΔNTCP

70%

0%

Dmean supraglottic = 10 Gy Dmean supraglottic = 20 Gy Dmean supraglottic = 30 Gy Dmean supraglottic = 40 Gy Dmean supraglottic = 50 Gy Dmean supraglottic = 60 Gy Dmean supraglottic = 70 Gy St-IMRT SW-IMRT

60%

2%

50%

4%

40%

6%

30%

8% D NTPC

ΔNTCP different in each individual patient

NTCP (%)

10%

20%

12%

10%

14%

0%

0 10 20 30 40 50 60 70 Mean dose PCM superius superior PCM

Patients

Langendijk, et al. Radiother Oncol 2013