Flow Cytometry catalog - US 2019
Single-Color Conjugated Antibodies
Analyte Specific Reagents - ASR product list
CD5 CD5 is a type I transmembrane glycoprotein with a molecular weight of 67 kDa. The extracellular domain consists of 3 scavenger receptor cysteine-rich (SRCR) domains of nearly 100 amino acids each. The CD5 is expressed at the surface of mature T lymphocytes, by most of thymocytes and by a subpopulation of B lymphocytes (B-1a) expanded in neonatal life, several autoimmune disorders and some B-cell proliferative disorders (B-CLL). It is not found on granulocytes, monocytes and platelets. The CD5 antigen is the ligand for the B-lymphocytes cell-surface protein CD72. The CD5 / CD72 interactions are involved in the regulation of T and B lymphocyte activation and proliferation. B lymphocytes can be divided into B-1 lymphocytes and B-2 (or conventional B) lymphocytes based on different localization, functional characteristics and gene expression. The B-1 lymphocyte subset is divided into B-1a and B-1b subpopulations, which do or do not express the CD5 antigen respectively. The B-1a CD5+ B lymphocyte subset expresses immunoglobulin with inherent low affinities for self-antigens.
Lysed normal whole blood sample.
Clone: BL1a
Isotype: IgG2a Mouse
BL1a monoclonal antibody (ref. 6T-CD5.5) was used as a CD5 reference monoclonal antibody during HLDA / 6.
Form
Size
Format
Part#
Status
Line Quality Standard
PB
A82790 IM0468U IM0469U A33096 IM2637U A70203 A51075 A60790 A78835 A78836
0.5 mL
Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid
ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR
IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest
GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP
FITC
2 mL 2 mL 1 mL 1 mL
PE
ECD PC5
PC5.5
0.5 mL
PC7 APC
1 mL 1 mL
APC-A700 APC-A750
0.5 mL 0.5 mL
Form Clone: CLB-T1/1
Isotype: IgG1 Mouse
Size
Format
Part#
Status
Line Quality Standard
ECD APC
B55387 B55386
0.5 mL 0.5 mL
Liquid Liquid
ASR ASR
IOTest IOTest
GMP GMP
If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 37 US Clinical Diagnostics Catalog
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