Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD137 CD137, also known as 4-1BB or ILA (for Induced by Lymphocyte Activation) is a 39kDa type I integral membrane protein of the TNF/NGF family. CD137 is expressed on activated T and B cells, NK cells, monocytes and follicular dendritic cells. Differential splicing leads to the release of a 16-kDa soluble from activated T cells. CD137 is involved in monocyte activation by inducing an increase in the production of IL-6, IL-8 and TNF- α , and an inhibition of IL-10 production. In addition, CD137 plays a role in the induction of B lymphocyte apoptosis and the co-stimulation of T-cell proliferation.

Lysed normal whole blood sample

Form Clone: 4B4-1

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

ECD

B76262

0.5 mL

Liquid

ASR

IOTest

GMP

CD138 The CD138 antigen (also known as syndecan-1) is a member of the syndecan family, which is comprised of 4 types of transmembrane heparan sulfate proteoglycans macromolecules (syndecan-1, -2 or fibroglycan, -3 or N-syndecan, and -4 or amphiglycan). These molecules are involved in interactions with extracellular matrix proteins, with cell-surface molecules and with soluble proteins such as cytokines. CD138 expression in human hematopoietic cells is restricted to plasma cells in normal bone marrow. Peripheral blood monocytes, T- and B-lymphocytes are not reactive. Tonsil cells and early B-cell precursors in human bone marrow also are negative. CD138 is expressed in a variety of mature tissues, including epithelial cells, endothelial cells, fibroblasts, keratinocytes and normal hepatocytes. CD138 may act as an essential regulator of ligand-specific activation of primary signalling receptors at the cell surface, by co-engagement of various accessory ligands.

U266B1 cell line.

Form Clone: B-A38

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PB

B37788 B42019 A40316 A40317 A98835 A87787

0.5 mL 0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP

KrO

PE

2 mL 1 mL

PC5

PC5.5

0.5 mL 0.5 mL

APC

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 86 US Clinical Diagnostics Catalog