Expert Review Panel for Dietary Supplements

II. Review of the Method Only 1. Does the applicability of the method support the applicability of the SMPR? If not, please explain what is missing. 2. Does the analytical technique(s) used in the method meet the SMPR? If not, please specify how it differs from what is stated in the SMPR. 3. Are the definitions specified in the SMPR used and applied appropriately in the method? If no, please indicate how the terms are used. 4. Does the method, as written, contain all appropriate precautions and warnings related to the method's reagents, components, instrumentation, or method steps that may be hazardous? If no, please suggest wording or option(s). III. Review of Supporting Information 1. Are the definitions specified in the SMPR used and applied appropriately in the supporting documentation (manuscripts, method studies, etc...)? If not, please explain the differences and if the method is impacted by the difference.

Yes. Authors tested one type of casein protein and one type of whey protein, which are listed in the Table 1 of SMPR. Authors also showed this method can distinguish target analytes from potential adulterants in two types of dietary supplements (pre workout finished goods and premixed vitamin).

Yes.

Yes.

No. Authors should demonstrate the safety of handling reagents and instruments when using this method.

III. Review of Information in Support of the Method

Yes.