Expert Review Panel for Dietary Supplements

V. Final Recommendation Do you recommend this method be adopted as a First Action and published in the Official Methods of Analysis of AOAC INTERNATIONAL? Please specify rationale.

Not until the weaknesses listed before are addressed. The method appears sound but it's true LOD/LOQ and chromatography need to be better described and evaluted to assure the method will meet industry needs. Analytical range of analytes in original materials need to be stated. Need system suitability for chromatographic separation. LOD/LOQ must be properly determined by spiking blank matrix at low levels. Clarification of 1:10 dilution of dried extract in the sample preparation.

Specific details for these are listed earlier in this report.

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