Nursing Catalogue 2016

141

Designing Clinical Research, Fourth Edition Stephen B. Hulley, MD, MPH 978-1-60831-804-9 • July 2013 • Softbound • 7” x 10”pp • 59Table

Designing Clinical Research has been extensively revised and continues to set the standard as a practical guide for doctors, nurses, pharmacists, and other health professionals involved in all forms of clinical, translational, and public health research. It presents advanced epidemiologic concepts in a reader-friendly way, and suggests common sense approaches to the challenging judgments involved in designing, funding, and implementing. Features • NEW! Approaches to sample size estimation, keeping it simple while covering more design options. • Examples and ideas on what’s new in clinical research. • Exercises that highlight major clinical research issues. • Treatment of clinical trial design and implementation. • Expanded and updated content in every chapter, with new material on: non-inferiority trials for comparative effectiveness research incidence-density case-control studies confounding and effect modification; diagnostic test studies to inform prediction rules; ethical aspects of whole genome sequencing; automated data management approaches; new NIH grant-writing requirements. • Color format, and Electronic access, powered by Inkling ™ as a free companion to the text; viewable through your browser or as a download to tablet or smartphone ; the complete text with optimized navigation; note-sharing, highlighting and bookmarking capability; cross-linking of references and content; rapid search options linked to the new glossary.

Research • Statistic & Theory

Table of Contents Section I: Basic Ingredients Ch. 1: Getting Started: The Anatomy and Physiology of Clinical Research Ch. 2: Conceiving the Research Question and Developing the Study Plan Ch. 3: Choosing the Study Subjects: Specification, Sampling, and Recruitment Ch. 4: Planning the Measurements: Precision, Accuracy and Validity Ch. 5: Getting Ready to Estimate Sample Size: Hypotheses and Underlying Principles Ch. 6: Estimating Sample Size and Power: Applications and Examples Section II: Study Designs Ch. 7: Designing Cross-Sectional and Cohort Studies Ch. 8: Designing Case-Control Studies Ch. 9: Enhancing Causal Inference in Observational Studies Ch. 10: Designing a Randomized Blinded Trial Ch. 11: Alternative Trial Designs and Implementation Issues Ch. 12: Designing Studies of Medical Tests Ch. 13: Research Using Existing Data Section III: Implementation Ch. 14: Addressing Ethical Issues Ch. 15: Designing Questionnaires, Interviews and Online Surveys Ch. 16; Data Management Ch. 17: Implementing the Study and Quality Control Ch. 18: Community and International Studies Ch. 19: Writing and Funding a Research Proposal