OMB Meeting Book_9-11-14
COMMENT PARAMETERS
USER COMMENTS
AOAC OMA
2011.10
Method Name/Manuscript Title
Vitamin B12 in Infant Formula and Adult Nutritionals High‐Performance Liquid Chromatography J. AOAC Int. 95, 313(2012); AOAC SMPR 2011.005 J. AOAC Int. 95, 293(2012)
Manuscript Reference
In your experience using the method, does the method perform according to the method’s applicability as written? In your experience with the method, is there any safety concerns identified while using or regarding use of the method? Do you have any information that supports regarding the reproducibility of the method as written: If so, please specify and submit information? Please attach any documentation to support your feedback, if available. Based on your experience with the method, are there any recommended changes to the AOAC First Action Method as written?
Yes
Fumes generated during mobile phase preparations (TEA and Formic Acid) and fumes from oven during heating of samples (cyanide).
None
Include a note that the method (all preparations) should be carried out under a fume hood and ensure that oven vent is connected to an exhaust system.
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