OMB Meeting Book_9-11-14
AOAC INTERNATIONAL Stakeholder Panel for Infant Formula and Adult Nutritionals (SPIFAN)
COMMENT PARAMETERS
USER COMMENTS
AOAC OMA
2012.15
Method Name/Manuscript Title
Total Iodine in Infant Formula and Adult Nutritionals by ICP MS
Manuscript Reference In your experience using the method, does the method perform according to the method’s applicability as written?
Sample preparation is by 5% or 50% KOH extraction and analysis by ICP‐MS for the range of 4 to 1500µg/100g. For 5%KOH extraction method, 5g slurry made up to 50mL (Total D.F = 80times). After extraction the solution so turbid, changed the color to brown and there is no clear solution obtained after refrigerated centrifugation or by filtering with 0.22µ filter. Further dilution of 10times more results final D.F to 800times. Method shows poor recovery for infant formula.
In your experience with the method, is there any safety concerns identified while using or regarding use of the method? Do you have any information that supports regarding the reproducibility of the method as written: If so, please specify and submit information? ‐ Please attach any documentation to support your feedback, if available. Based on your experience with the method, are there any recommended changes to the AOAC First Action Method as written? ‐
Extraction Method needs improvement. A different extraction proces is recommended with the use of different reagents.
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