AOAC SPIFAN Nutrients ERP-Final Review (Jan. 2019)

FOR EXPERT REVIEW PANEL USE ONLY NOT FOR DISTRIBUTION

Expert Review Panel for Infant Formula and Adult Nutrition Evaluation of Method - 2015.10 (Reviewer 2)

Title: AOAC Official Method 2015.10 / Free and Total Choline and Carnitine in Infant Formula and Adult/Pediatric Nutritional Formula / Liquid Chromatography / Tandem Mass Spectrometry (LC/MS/MS) First Action 2015 Author: Reviewer Name: Reviewer 2 Summary of Method: Method Scope/Applicability: This review is for the choline portion of the method only. The SMPR for choline simply references “determination of total choline”. Although the method outlines the determination of both free and total forms, and MLT data was included for both free and total forms, the final evaluation for suitability was made strictly against the SMPR requirement for measurement of total choline. General comments about the method: Method Clarity: Method Safety Concerns: Pros/Strengths: •

Cons/Weaknesses •

Supporting Data • General Comment:

Method Optimization:

• Performance Characteristics:

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