BCRB 2018

The concept of repair saturation Michaelis-Menten kinetics

Totally saturated

Velocity of repair V

A

V

V max

V =

max

+ A

K

m

Partially saturated

½ V max

Totally unsaturated

K m

A

Amount of damage

Michael Joiner

Basic Clinical Radiobiology 2018

Page 20 of 26

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